Systemic Lupus Erythematosus - A possible treatment
Summary: Lupus is caused by a defect in the body's auto-immune system. It is characterized by muscle weakness, arthritis caused by a the deterioration of the body's connective tissues, as well as attacks on other organs. Because of the non-specific nature of these connective tissue breakdowns it can be difficult to diagnose. When treated with Chloroquin, tunnel vision can result. Because of its inflammatory nature, it conventionally invites treatment using corticosteroid such as Cortisone or Prednisone. In some cases, may bring on epiliform attacks, induced a combination of excess insulin and hypoglycemia. As a patient may be overly sensitive/or is already producing too much corticosteroids, which has led to the slow degradation of connective tissue and cartilage, more corticosteroids can attack the shoulder or hip joints.
Another treatment involves the use of Aralin (Chloroquin) which can cause damage to the eyes. Because the unbalance in the immune system Lupus often appears before pregnancy with little or no effect on the unborn child. It is thought that some factor is released during pregnancy that is designed to protect the fetus. After birth, that factor is no longer present, and lupus returns..
A characteristic of lupus is sensitivity to ultra-violet radiation in sunlight that can further weaken the immune system.
A possibility may exist that the normal linkage between tryptophan and serotonin may be defective as the normal effects of SSRI's seem, at times, to be reversed. A clue to this is based on Lupus going into remission during pregnancy when the body produces an enzyme named IDO, which seems to block tryptophan. When it is not present, T-cells cannot reproduce. This might be a clue to auto-immune diseases such as Lupus. A supportive link is the deep depression found in Lupus patients and the sudden gain in strength during pregnancy.
Another possible link may be misfolding of certain genes in women and truncated genes in men. A clue might be found in dendritic errors.
Presenting symptoms: Any group comprising rheumathroid arthritis, ataxia, poor circulation, nervous manner or nervous exhaustion, muscle weakness, coughing accompanied by chest pain, sunlight sensitivity that produces rashes and/or fever, hypoglycemia, anemia, possible stuttering, a history of recurrent eyestrain, headaches on wakening, depression and/or panic attacks. It is identifiable by raw appearing red areas on the cheeks and forehead, together with inexplicable fatigue, persistent bruising, T-cell and blood protein abnormalities, that can be diagnosed by an antinuclear antibody test.
A Creatine test may also be useful as Lupus can affect kidney function. Possible lower levels of Coenzyme Q10. Possible above normal levels of Monoamine oxidase (MAO) and/or a low level of L-tyrosine and/or an unstable serotonin chemistry.
Elevated homocystene levels are possible. Possible link from dyslexia and Meares-Iren syndrome or taste acuity may be diminished. A higher or corticosteroid or insulin level than normal may be present.
Supporting familial symptoms: Tuberculosis - Pneumonia, Diabetes - heart problems - anxiety - excessive anger – a tendency for bipolarism and/or attacks of panic - short stature - retinitus pigmentosa - susceptibility to yeast or fungus infections - possible yeast or carbohydrate intolerance - Celiac - Autism - possible lactose intolerance - possible Protein intolerance - possible intolerance to soy proteins scleradermia - smoking.
A possible link may be a lack of normal levels of viamin D, as exposure to sunlight can accelerate lupus.
Many attempts at effecting a remission or a cure, may have been unsuccessful as they might not have realized that lupus combines elements that are usually associated with either the young, or with the aged.
It was with these thoughts in mind, that in 1982, an attempt was made to seek a workable solution.
It was based on the premise that lupus was contracted by a synergistic group of precursors, that, taken as separate entities, would not, of themselves, have such a debilative effect. As stress levels in modern society increase, so should the rate of lupus, increase.
In trying to find a set of common factors, we started with the curious effect on serotonin related production of l-tryptophan. Perhaps the apparent low effective serotonin level in the patient might have been because the serotonin was somehow (because of an abnormality in the cerebral neurochemistry) producing too much l-tryptophan (with a x-line factor as well)!
These hypotheses were worth investigating!
As any treatment with l-tyrosine can cause similar effects, the same caution is applicable!
The problem is how to reinforce the immune system without triggering hyperactivity. Some method has to be developed to retain normal immune system response while preventing the patient's own immune system from attacking the patient's own body!
It was felt that investigating a child's immune system response to its mother's body, some insight could be gained! Prospective mothers who have lupus seem to be in a temporary remission during pregnancy, only to have it reappear after their baby is born.
We decided after several years of study, that perhaps the action of l-tryptophan might lead us somewhere.
(What follows, seems to fit many of the problems associated with lupus. To some extent, this might also have some application to myasthenia gravis, ALS, MS and the other autoimmune afflictions.) If we postulate that the enzyme IDO blocks the abnormal action of l-tryptphan and the overactive t-cell production that is the consequence - perhaps this might lead to be a 'cure' for some auto-immune afflictions! AA0.1
But inspection of the literature shows a strange "linkage" between abberations in melatonin, low levels of serotonin, low levels of GH and low levels of Vitamin B6. In addition there seems to be an aberration in the hippocampus and a reversed reaction or overreaction to such SSRI drugs as Prozac.
There might be a clue in the overreaction to sulfa drugs, which in some patients, can produce a very severe skin shedding when sulfa drugs are utilized to treat Campfor Bactus. Some doctors have found the sulfa drugs can cause a flare-up in lupus.
Large (over 150 mg) Vitamin B6 may lead to a major decrease in the effects of any l-tryptophan especially when taken with zinc and vitamin B5 and Vitamin B12. Remember, that in doses over 250 Mg of B6, the minor calming effect seems to be absent although the SSRI effect increases! Much more study still remains!
Terminology can be confusing. Consider the situation with allergies. Some allergists state that patients cannot, a priori, be allergic to perfumes because perfumes contain an essential oil rather than the pollen of the flowers used in the preparation of the perfume. This is cited as a justification for the inclusion of perfume-strips in some popular magazines. This takes place in spite of reader's protests that they feel faint, nervous, or have headaches, because of the inclusion of the strips. These allergists ignore the fact that some perfumes contain synthetic organic chemicals that were selected for their stability. In many cases, these are not easily metabolized both may break-down into unexpected fractions. Because of budget limitations, not all possible side effects can be explored.
As there is not a serious "common element" present all the time, such complaints can, all too often, be ignored.
Therefore, such cases that occur, are dismissed as being psychosomatic. There seems to be a ever increasing need, among specialists in many professions, to attach labels. By doing this, experts may be presuming to know with what their dealing. Anything else can be ignored as irrelevant!
What may not be appreciated is, using the case of migraines attacks as an example, that in this instance, those perfumes are 'triggers,' in much the same way that MSG is a trigger. At low concentrations, it makes people apprehensive or nervous. At higher levels it may cause migraines 1, or, in the case of serotonin aberrations,
panic attacks. Both migraines and panic attacks have been linked to an imbalance in the level of serotonin and prostaglandin's in the brain. The serotonin in the blood platelets causes the arterial contraction and then the dilation, the prostaglandin produces the inflammation. Lack of sleep, or stress, raises the level of prostaglandin's and the lead to a condition of hyperhomocystene.
But panic attacks, could be caused by a CCK DN.00.00(cholccystokinin) neurotransmitter defect which could be linked to a malfunction in the brain's misuse of SSRI's. A possible co-factor, may be an altered succeptability to sensory overload!
In young children, the use of MSG appears to cause some cases of ADS (Attention Deficit Syndrome), asthma, and heart arrhythmia. For some of the children, even soybean protein derived milk substitutes such as Prosoyba (tm) may be counter-indicated. There may be a link to Celiac disease, Gluten and/or Yeast Intolerance! The FDA stopped the use of MSG in baby food. However even such things as some soups, some potato chips, and other basic foods, may use MSG (or autolized yeast, etc.) in their manufactured products.
There appears that no study has been made to search for any possible correlation between the use of MSG and Ritalin(tm).
A major concern is the apparent increase in the number of excitotoxins that are now a major portion of a childs diet. The so-called fast food outlets are decreasing the amounts of trans-fats and it is hoped that the number of added preservatives may also decrease. The question has to be asked, "just how many preservatives have to be taken out of the food so that it is still save to consume - allowing for the delays for when it is produced until it is consumed?
Stress can also cause other immune system problems, by possibly decreasing the effectiveness of the blood-brain barrier, thus allowing defective DNA or the fragments to affect the brain itself. This may be why people who live in a "happy" environment seem to have less heart attacks, less strokes and less arthritis.
It also may be the reason there is about a six-month delay in the development of even disease such as pneumonia, viral attacks, and even severe depression!
Unfortunately, a lower than normal level of serotonin can cause timidity, and the inability to form close personal relationships. There is the ever-present fear of being criticized or judged.
Perhaps, some of these are even the side effects, such as hypoglycemia, of the antimalaral drugs used in treating lupus. These may have not been considered fully. As a result, any general panic or depression is regarded as a "just another cause for having contracting lupus". There does not seem to be a simple genotype which can be identified at this time. Some people seem to have an ability to "roll with the punches" of life, and others don't. Childhood stress seems to play an important part in the ability to withstand stress, and this is often overlooked by doctors, especially male doctors!
Some doctors, frequently confuse the depression in lupus, with being depressed from overwork or stress. They advise patients to change jobs. They often fail to take into account that the very thought of changing a job, can be very stressful in itself!
As another possible common factor, of the headaches of hypoglycemia, photophobia is sometimes present in severe headache attacks, as are sensitivity to loud noises, ataxia, nausea, syncope, and vertigo. Hypoglycemia CC1, especially in females, appears to be tied to a low (somatropen) growth hormone (GH) level, melatonin, sometimes lactose intolerance is present, as well as dyslexiaCC2 . Hearing function may be affected including an a apparent inability to differentiate between the sound of someone speaking and noise.
It is now increasingly accepted that a low GH level may be related to the amount of a baby's cuddling and/or the mother's apparent neglect of the child at the emotional, or "bonding" period. Children who are loved gain more weight, have less psychological "hang-ups", and adjust to life's problems much better. This may be why, pets may play an important role in emotional adjustment. Such children seem to develop an high degree of empathy to other people but they have to have it returned to almost an unnatural extent, to feel loved. Quite obviously, other children don't feel the same emotion, or don't feel it to the same degree. This is probably why getting tagged with being "sensitive" has such adverse connotations.
The consequence, is that such a child may become a "loner" and may swing back and forth between fear and dominance, in alteration, embracing first the left hemisphere's and then the right hemisphere's mode of thought (0r the reverse)! This may be have the serious consequence of increasing any latent degree of bipolarism!
As children mature, this pitfall may widen even as it grows deeper. There seems to be less reason to accept people as they are.In simple terms. And once they are classified as bipolar, the gulf deepens! Their defense mechanisms go into overdrive. In some countries "eccentrics" are not scorned. Society has apparently forgotten that many of the most brilliant discoveries have been the result of such aberrations.
But if they sense that they can never be accepted by their peers, they might become "true believers", prophets, or even zealots! They think that whatever is not totally correct, has to be totally wrong! This toggle-effect may, in time, in time, cause someone such as this, to loose all sense of humor.
The very antimalarials uses to treat lupus, as we said previously, can excaberate depression. This can lead to major psychological problems for the patient being treated for lupus. They may need more than a casual level of support. Most doctors don't realize this!
In extreme cases, the "victim of lupus" (and I mean this term), may develop the rather extreme need to abandon everything (including possessions) and run away. If they are not able to handle the extra stress of the antimalarials, they may find something inside of them, that will enable them to survive!
This, may cause them to become "control freaks" (which can result in a tendendy to 'bully' other people). In turn, they will start to become a problem with other people in the company. They try to work harder, pay unnecessary attention to minute details, and thus are constantly behind in their work! In compensation, they try to work harder, and may feel it necessary to work on weekends and even avoid holidays. The results are that they feel that their hard work is not being recognized!
This will sometimes make them want them to "try and take-over" every job, even to the point of disregarding the proven competence of others! then, like the aggressive driver, they spent too much time in "spinning-their-wheels", cutting in-and-out of other driver's lanes (jobs) and getting nowhere!
In a similar fashion, people may say they are allergic to lactose, when they mean they are lactose intolerant. Patients who suffer headaches (or migraines when they consume too much complex carbohydrates or foods containing certain prostaglandin's) may be complex carbohydrate intolerant, and may be gluten intolerant (Celiacism). It is probable that a person with lupus is serotonin deficient, perhaps because of a defect in protein conversion which can cause depression and panic attacks.
(Hint: In the Canadian Maritime Provinces someone has opened a bakery that speclizes in gluten free foods. Because the woman had a serius reaction to gluten she researched for several years and was finally able to make a host of items that tasted excellent and were all gluten free. Now she is distributing her products coast to cost in Canada and is exporting to the US.)
There may be a deficit in their body's production of vitamin B6, leading to a susceptibility to yeast infections, and/or fungus infections, which may be a link to hypoglycemia. It is also a possible link to the lower production of serotonin as well as a possible link to a l-dopa abnormality.
A yeast infection can produce a while series of side effects, such as vertigo, panic, depression, loss of short-term memory and other, unexcited side effects. The CEIA test (Candi-sphere seriodiagnosis analysis) for yeast infections should be performed.
Lactose intolerance has much the same etiology as Celiacism, so much so that a parent who is lactose-intolorant may fail to recognize the development of the adult phase in herself or himself. One common element is headaches, nausea, or even depression. these also may be linked to yeast problems. It therefore, often difficult for doctors to grasp the entire pattern of lupus!
The study of hypoglycemia has suffered because of over popularization in the 70's. In this respect it is similar to migraines. Initially, migraines fell into disrepute in the 1930's due to an ill conceived study that attempted to define a migraine personality. Those persons were presumed to have a neurosis that would respond to psychiatric care. Unfortunately, there was an element of truth. Many patients were counseled to switch to less stressful occupations 4 and some of the migraines stopped. However some migraines were caused by other more serious factors. In the case of weather related migraines, they may tied to latent or potentially active cerebral aneurysms, or more simply, a result of blood vessel constriction/dilation cycle.
Extreme cases of hypoglycemia may lower the body temperature so much that the person exhibits the classic signs of hypothermia, slow pulse, difficulty in walking, hand tremor, vertigo, slurred speech or even stuttering! Observers may even think that the people are drunk! But the same symptoms are present in yeast infections as well. Occasionally, the yeast in the body, will combine with sugars, to produce more than methane. It can produce ethanol as well. In this case, people who never touch alcohol, may have so high a blood alcohol reading, that they can be charged with drunken driving! In this case, they may have, literally, severe hangover types of headaches. Drinking a lot of water the night before, will reduce the brain swelling and mitigate, if not stop, the headache. Patient's with yeast infections, may have hypoglycemia, as the infection is fueled by sugar. When the blood sugar gets very low, the condition may remain stable! As patients with lowered immune system levels may not be able to fight off the infection.
People with hypoglycemia, may have less difficulties with classic allergies. But they can still have some problems with chemically or visually -induced triggers. On the other hand, when a patient sees to have developed allergies to a whole host of substances, a doctor should suspect a yeast infection, a fungus infection, a protozoa or even a combination!
An inspection of medication used to relieve migraines will probably show that similar medications are used for hypoglycemia, headaches, vertigo, nausea, antidepressants, tranquilizers or high blood pressure.
Even condiments or spices such as horseradish (hraine), pepper, ginger, paprika, mushrooms, mustard, chili-peppers, Tabasco sauce, Wostershire sauce and capsinin-containing foods such as Japalino peppers, may be in common use an alternative to salt. Most of these are now recognized as an anti-inflammatory agents. But they are also effective against yeast, fungus, and protozoa infections!
The search of accepted texts on hypoglycemia together with the equivalent reference texts on fungus and yeast infections will reveal too many similarities to be coincidental!
Even some gardening manuals will reveal the same so-called "cures" for moss and fungi!
The hypoglycemic patient might be lacking in a normal level of bile or stomach acid. That is why, for them, considering their possible yeast intolerance, antacids may never work. They may be especially fond of some foods or condiments (such as) pickles, because in some cases, their acidity may an aid to digestion. Frequently these people's work habits make them prone to stomach ulcers. This is why they should be tested and, if necessary, treated for e-pilorii bacteria that their marginal immune system may be unable to handle. However sulfa drugs should be used with caution.
There is a possibility for an alteration in the traditional method of dealing with pre-diabetic hypoglycemia. When, upon awakening, the body as accumulated the essential bile acids, the patient may be more able to handle a normal breakfast. As the level of available bile decreases thereafter, less food is needed If too much is food is consumed, indigestion will result!
As lipids carry the energy in the bloodstream, too few lipids can seriously affect their metabolic by-products, in such things as testosterone, prednisone, etc.
As a possible result, mild hypoglycemia became an essential for survival. (just as in the case of the Navaho and the Australian aboriginal). In the case of the first two, a near desert was involved. There may have a concentration of minerals in the desert sand. I would expect to find zinc, copper and chromium among others.
Some bacteria and fungi have the ability to extract needed nutrients such as minerals, to grow. This may be the case in "Manna" and it might also be true of certain cacti in Arizona which provided potable water. Another possible link is Aloe Vera, a desert plant, which is effective against sunburn and is thought to increase insulin production.
Another pattern is found in the use of garlic to stop fungi or moss in grass! (It is also worth making a comment upon the language of the Navaho which sounds like Hebrew).
We cannot afford to overlook anything by which we could gain insight. For example, a similar sort of story is found in England in the form of the mushroom 'fairy circles', which were revered. A fairly common problem among researchers world-wide is over specialization. The joke is that when a scientist become a specialist, soon he knows everything about nothing and looses his effectiveness.
Because of the "necessity" for peer review, new approaches to a problem are too often dismissed by the "experts".
Because inbreeding with other parallel thinkers is a survival trait, a close inspection of family names and physical characteristics may hold some unexpected surprises.
Because any people who embraced the 'legends' survived, often because
of the parallel thinking (or the use of their quick wits), they were often
at odds with the serial thinkers who regarded them with deep suspicion
and frequently attempted to subject them to inquisitorial actions to confiscate
their wealth!
Female patients who have lupus, may find that their body, during pregnency, produces a drug that alters a woman's immune system to protect thr baby's immune system against l-tyrosine. After the baby is born, there may be a sudden reduction in serotonin. This may be linked to a sudden alteration in the hormone system (the cortisol level may alter) that makes the mother suseptable to the "flee or fight" syndrome to protect her child! As such a mother can suffer 'post partum' depression, her blood insulin level may rise even more, leading to the epiliform attacks.
Eating a diet high in carbohydrates , is generally is a way to increase the level of of tryptophan. As such a diet may reduce some of the other essential amino acids such a diet increases the insulin level in the bloodstream. The result can be insulin seizures! They may be prevetable by the use of a (high fat) ketogenic diet.
This may be the familial link to diabetes.
There is a major dietary problem that ensues. As the energy is parially based on the essential lipids in the diet, the typical patient may be lacking in muscle strength and the stress level may be so high as to make the patient's hair thin, friable. and laking in luster.
Now, with these factors in mind, you may proceed.
Although a hereditary common factor in lupus may be rheumathroid arthritis, another hereditary item may be a family history of diabetes, heart problems, cancer, or indeed, any of the autoimmune, or neuro-degenerative diseases. All may require an unstable HPA axis and cortico-steroid unbalance.
Much has been discussed about chlorine from industrial effluents, as a possible link to breast cancer. However the chlorine used in bleaching wood pulp may not be the culprit! A more likely candidate could the bis-phenyls, especially nonyl phenyl. Racial Carson linked DDT to genetic problems in birds. But PCB's are also mutagenic. Could there be an interaction between DDT, PCB's and dioxin, where the cumulative effect is much greater than the sum of the parts? One has to wonder whether diallyl phthalate (a common plasticizer) is involved as well?
Estrogen like chemicals can be a major problem, for they may be difficult for body to convert. In other words, they may be so stable that they cannot be converted in the normal fashion, to simpler, less irritating materials. We may have encountered synthetic perfumes that resist the normal process of breakdown, and, what is even more serious, can cause unexpected side effects such as chemical sensitivities, migraines, vertigo or nausea!
Because the demands for proteins by hypoglycemia, which may break down protein to boost the drastically low of level blood sugar (glucose), the breakdown may affect all the sources for protein in the body, including the muscles, the connective tissues, the myelin sheath on the nerves (singly as in multiple sclerosis, in toto, as in myasthenia gravis, or selectively as in ALS - in the stomach or bowel, and Lupus). The consequences may include any form of arthritis!
Another possible hereditary factor for Lupus, may be a erratic level of melatonin CD01 . This could result in sleep difficulties, produce a susceptibility to autoimmune or other neurological problems, such as is the case with lupus, or depression/panic attacks, which may also be liked to a lower than normal level of vitamin B6. As a lower level of melatonin, and/or vitamin B6, may be linked to lower level of somatropen - growth hormone (GH), there is a possibility of diminished height as well. A low level of melatonin is also linked to retinitus pigmentosa CD01.01
Another common factor may be an elevated level of insulin production by the body. This could show-up in the patient's having a tendency to be overweight in spite of an overproduction of the human equivalent of Leptin CC3. This, together with an elevated level of prostaglandin's, and hypoglycemia, could a common factor in cancer, DF00.01heart attacks, or strokes, and, in addition, an increased propensity for diabetes! The patient could have problems if there was too many carbohydrates in the diet, as they might be a factor in the severity of headache attacks. In extreme cases, the patient could even be Celiac. Indeed the ratio of protein to carbohydrates may have to be adjusted in favor of an increase in protein! As too much protein may result in possible increase in intestinal cancer, unless extra foliate (folic acid+vitamin B12+vitamin B6) is supplemented in the patient's diet, this forms another hereditary factor.
The presence in the fetus of high levels of growth hormone (GH), folic acid, and vitamin B12 as well as some factor that blocks the normal action of l-tryptophan could be a clue to the apparent non rejection of fetal tissue cells. This, in itself, could pose a clue to a way to mitigate tissue rejection in transplants! Consider, what is difference in the GR reaction in males and females? As a result could a man be more likely to contract a disease where low GH was not a factor?
There may be another factor as well. Attention Deficit Syndrome (ADS) might be present. Watch for the inability to remember whether such things as , for example, a stove is off, a door locked, or even an appointment has to be kept. This type of behavior, in children, is conventionally is alleviated by the use of Ritalin. This seems to be caused by an oversentization of the hippocampus by repeated stress reactions.
A possible alternate might be to raise the patient's l-dopa level. As this presupposes a family history of a general deficiency of the B vitamins, look for either bi-polar illness or even schizophrenia where habitual smoking raised the dopamine level too much!. This may have been overcome by developing a over intense ability to focus on one aspect of a problem, to the exclusion of other, more important factors! This, in turn, might cause business problems as too much time is spent in pursuit of trivia! The patient may be addicted to chocolate, coffee, or smoking. These may help them to "maintain focus".
Lupus may require several factors to act together before it manifests itself. It has been argued that some cause of depression (that causes an immune system dysfunction) must be present a priori, or whether lupus itself produces the depression a posteriori. As noted, a chronic lack of sleep can weaken the immune system, as can excessive exposure to the UV rays of the sun. However, any doctor needs to recognize the side effects of antimalarials!
In a similar fashion, hypoglycemia can be inherited or self-induced. The abnormal protein present in the blood of lupus patients may be a recessive factor that manifests itself only when a person has a weakened immune system. The dry reddened skin on the cheeks and the forehead is a sign of a minor circulatory problem similar to the reddened cheeks of someone exposed to low temperatures. In cases of severe hypoglycemia where protein is lacking in the diet, the body may draw on its own protein reserves from muscles, connective tissues of cartilage. This, in turn, may be caused by a lowering of the body's coenzyme Q-10 (CoQ10). AA1
Although it seems unlikely, the presence of a genetically altered brain chemical may result in a analogue of procainamide in the brain. However, unlike procainamide itself, which can result in a form of lupus 6.4b6that might possibly be different from "true lupus". (see the comment on procaine therapy). Again, it is the presence of several overlapping factors that may cause lupus.
Because of hereditary factors, hypoglycemic's may have one lazy eye, or be legally blind in one eye. They may have been dyslexic, or just a 'slow learner,' a day-dreamer, be minororally autistic. The patient may have learned to read a language that is normally read from right to left (where it is a survival trait) or have been able to read only in columns. All these are symptomatic of hereditary hypoglycemia and all are linked with hemispheric dominance in the brain. Of course, hypoglycemia can be induced by such things as alcoholism, cancer, and work or study induced stress.
A typical Lupus patient may, as an adult, exhibit some childlike qualities, such as an unusual gift for languages, writing, art, or music, all of which require a facility for parallel thought processes.
Stress is involved in Hypothalmus-Pituitary-Andrenal (HPA) axis and cortico-steroid inhibition. Any instability in the HPA axis, may lead to elevated cortico-steroid production and consequent immune system problems that may be triggered by hypoglycemic stress.
Hypoglycemia increases susceptibility to infections, including neurological diseases which is why herpes-zoster (shingles) infections are an indication of hypoglycemic nervousness or stress whenever a patient has been infected with chickenpox. This also can be caused by an immune system that has been weakened by an exposure to some substance causing an allergic over-reaction.
Other stress related events such as heart attacks, and strokes may require a combination of high blood pressure and cholesterol to attack. All require a homeostatic (hyper homocystene) imbalance involving HPA axis problems.
As stated, hypoglycemia frequently can be induced from lack of sleep, job stress, the stress of studying, alcoholism, drug abuse, some social diseases, or several factors in common, including hereditary factors. There is no other common factor, except that induced hypoglycemic's are more likely to be linear thinkers. Hereditary hypoglycemic's are more prone to be parallel thinkers, and may as well suffer from depression, manic-depressive syndrome or panic attacks. They frequently fond themselves in professions requiring great creativity such as the arts, teaching, and sales where their parallel thinking can lead to an unusual degree of success. A GTL (glucose tolerance test) is useful.
The mild "high" of hypoglycemia can become just as addictive as alcohol. Doctors may misdiagnose it as an addiction to alcohol. This is why people can become workaholics. However it may be involuntary. Because it can lead to depression, the patient is driven to succeed and work harder rather than learning to working smarter! Frequently small mistakes will appear overwhelming and the patient could suffer a stroke or heart attack because of an elevated CRF (corticotrophin releasing factor) level!
In much the same way as an addiction to being a workaholic took place, an addiction to tobacco may have developed. MRI scans have demonstrated that Nicotine alters the brain chemistry by increasing the neurotransmitter (Dopamine) that makes smoking such a pleasure. At the same time it also inhibits the Monoamine oxidase B (MAOB ) that lowers the dopamine level AA01.7. As a high level of Dopamine seems to mitigate the severity of Parkinson's Disease, it might account for the reduction in that disease among heavy smokers! It has been suggested that treatment with St. John's Wort (Hypericum perforatum), or even selegiline, either of which are MAO inhibitors, may lessen the depression and other aspects of lupus. (Anti-depressants are often a combination of several drugs, (SSRI's) which act to raise serotonin levels, by acting as an MAO inhibitor.)
The amino acid L-tyrosine passes the blood-brain barrier and is converted by the dopamine producing neurons, to L-dopa, and then to dopamine in the brain, which accounts for tyrosine's beneficial effects - including resistance to cold, depression, stress, and hyper-active nervousness. It also is a reason to watch its use in treating depression! Researcher'sBC1 efforts, resulted in segaline (also known as depranyl). Related drugs may also find use for Alzheimer's, but they may produce the sometimes life threatening "cheese" effect and are potentially dangerous when combined with alcohol. Indeed, some non drowsy anti-histamines also have the same dangerous potential.
Consider the case of FenFluoramine in weight loss programs. It can cause serious hypertension in the lungs in a minority of patients. Several similar reactions may have been caused by antidepressants containing fluorine.
Check the patient's tolerance to cold. If it is high, there may be a risk of overdosing with vitamin B6!
However, the cigarette tobacco smoke BB1 also destroys much of the tocophrerols, cartenoids, and retinol, possibly leading to cancer because of a lessening in the natural immunology.
See also the cautionary reference to PABA - DMAE - Procaine 6 ** .
Indeed, depressed persons have less of the neurotransmitter Phelylethylamine (PEA) in their body fluids. DL-phenyalalanine (DLPA) inhibits the enzymes that destroy endorphins, as well as raising PEA levels. Vitamin B1(cobalamin), the amino acid DL-phenyalalanine (DLPA), and methionine, may prove effective. Hypericum perforatum, (St. Johns Wart) whose active ingredient is Hypercin is held in esteem in Europe as a mild non-prescription antidepressant which has less side effects than most prescription drugs. Methionone also acts to ward off fatigue by converting norandrenaline into adrenaline.
The habit of smoking may ensue even if the other needs of the body are satisfied! Formerly, people in tobacco-growing areas might have suffered from pellagra because growing tobacco depleted the soil and made it vitamin B3 deficient. Tobacco contains nicotine, related to (Vitamin B3) and the body may well come to depend on it to reduce the nervousness caused by mild overwork (mild hypoglycemia). Dopamine has also been used to reduce depression. An obvious substitute for smoking is taking nicotinic acid - niacin. Unlike tobacco smoke that contains damaging tars, niacin increases circulation and to some extent relieves the symptoms of tension by stabilizing the blood pressure.
It is not the tobacco that reinforces the craving, although a habit may ensue even if the other needs of the body are satisfied! Tobacco contains nicotine and the body may well come to depend on it to reduce the nervousness caused by mild hypoglycemia. Endorphin enhancers may be necessary as well.
A possible substitute for tobacco is nicotinic acid - niacin. Unlike smoking, niacin increases circulation and to some extent relieves the symptoms of hypoglycemia. By increasing the glucose level. It has another beneficial effect as well. Taken twice a day in 500 mg. doses (in a time release form to reduce the flush reaction) it can also cause a steady reduction in cholesterol! Taken with lecithin (in 10 grain amounts) it has been postulated as a treatment for inner ear caused vertigo - much the same as ginger. But where adult onset diabetes may be a problem, the patient may have to take chromium picolinolate as well!
Another possibility involved with MAO inhibition by nicotinamide, involves its apparent effect in switching off the gene that may cause diabetes as well as lessens the memory loss effects on people with Alzheimer's.
Women seem to suffer from SAD more often than men. It has been postulated that this may be caused by a light deficit response by the pineal that leave an excess of melatonin behind in the female brain. There may be a link to a lower level of Vitamin D as well as a low level of calcium. Remember, in nothern latitudes, the level of light may may lead to a disfunction in the pineal gland; look for a succeptibility to arthritus, ostiopina and fractures. These might be the result of the low daylight light level causing a deficiency in Vitamin D and serium calcium . Even though arthritus is a misuse of the calcium in the body, if it is too low the body will take needed calcium from the bones. The lack of Vitamin D weii excaberate this! Therefore, it may be prudent to limit the administration of oral melatonin to the late spring, summer, and early fall.
There has been an immense amount of work on the differences in DNA between women and men. The DNA in men has an increased tendency to break into smaller fragments that have a tendency to attach themselves to the ends of normal DNA. This may be why men or more susceptible to some form of diseases which can be more readily avoided in women. With men, there appears to be a more intense need for antioxidants to allay the problems of gene fractures and a propensity to have problems caused by recessive genes.
Hereditary hypoglycemia (genetic hypoglycemia) can generally be classified into two groups, high GTL and low GTL. A typical high GTL group may be descendants from Yorkshire families where the tolerance to cold may be because of a high level of tyrosine. In Yorkshire a different manisifation of Hypoglicemia may occour. Here the lowered level of glucose might be caused by a yeast related problem where any type od 'suger' is consumed by the abnomally high level of yeast. Most often this is manifested in woman, however in men having a non-acidic metabolism. A possible clue might be a man that never suffering from heartburn. The bile level might be so low that normal digestion is difficult. The patient might think that he is suffering from a heart attack. A test may reveal that it is nothing more than a gas buildup caused by undigested food. At one time, doctors had these patients take a low level of acid. Now the treatment is taking two acidophilus capsules before meals. Unsweetened yogurt may help.
In severe cases candesis infections may result. The treatment can be very severe and might be banning all foods that contain yeast, inchuding simple carbohydrates. Sometimes a minor yeast infection might be stopped by a very dilute form of vinegar. However, a unsweetened yoghurt douch might be indicated.
In more extreme cases, a form of yeast might be encountered in acidic soils where summer vacation cottages have been built. Here the yeast spores might be inhaled with a consequent severe lung infection. This condition is so rare that it might not be propery diagnosed and death might occur.
A person with a high GTL and a high L-tyrosine level is less affected by the cold - and may suffer because of being unaware of the cold.
A person with a low GTL may be descendants of Semitic, Baltic or Mongol families. The patient might also have Thysellonic anemia (Thalaseslemia) BA1.14. In like fashion people with a low GTL may feel the cold and frequently crave a diet rich in fats. If hypoglycemia is present a basic blood sugar test will reveal it. If present a glucose tolerance test should be performed to show if the (GTL) glucose tolerance level is high or low.
If hypoglycemia seems to be overemphasized, it is because it, a HPA and cortico-steroid inhibition dysfunction, play a part in the development of Lupus. In addition, it may even be linked to hypoglycemia brought on by constant use of aspirin or any medication based on quinine. This argued for the addition of both vitamin E as well as vitamin C to the diet if cataracts are to be avoided.
In effect, in lupus, as well in the use of the treatments of lupus by using antimalarials, the normal feedback loop of Homeostasis is not functioning properly. This should not be inferred as a case for using steroids as anti-inflammitories as these can result in further loss of bone and actually increase arthritis!
Other serious problems that could occur are epiliform attacks, brought on by the low glucose level of hypoglycemia interacting with sudden changes in PO2, possibly because of sleep apnea. Another somewhat more remote possibility is a history of severe headaches resulting in ketosis. As an example with migraines, (the probability of severe migraines in a patient with a low level of serotonin is minimal), nevertheless, when the frequency of the migraines are reduced, the ketosis is reduced as well. If the seizures start about the same time, they were probably brought on by a prolonged, healthy, low fat diet resulting in absence of the ketones that accompany a loss of weight due to fat or the inability of the serum lipids to act as a source of energy! Sometimes, it is forgotten that some form of lipids are needed to carry the energy. Often, it seems as if there is a constant state of hormonal war, in a patient having lupus.
As there is a link to an increased production of insulin in the body, any epiliform attacks, or seizures may have been a form of insulin shock This may not show up on an EEG, even when flicker is used.
Thus, there is the distinct possibility of the body's over-production or insulin or corticosteroid, causing an edoctrinal imbalance that may lead to micro seizures if not seizures themselves! It may be that the ketones were inhibiting the seizures. The treatment is to substantially increase the fat in the diet, with only the proteins necessary to avoid hypoglycemia. The patient must be on a diet that will produce ketosis!
This, in children, involve a ketogenic-diet!
As parallel thinkers sometimes are subject to seizures, they may have too short a neurotransmission time, and as a consequence, may lapse into a form of positive feedback thus producing a seizure!
Because the lupus patient probably is deficient in serotonin, they are prone to panic attacks rather than migraines.
(Where there are a hereditary seizures, they may be due to a shorter path length or a faster response in the brain, suggesting a higher level of insulin as a cause of seizures. This argues for a faster response time for complex problems, or a parallel form of thinking, where there is not the buffering effect of a time lapse to prevent most of the brain's neurons from triggering at the same time! Where there is a possibility of manic-depressive thought, the entire "dual brain" triggers for epiliform atacks, may not be present as the deay might allow the triggering impuse to dampen down)
To continue, survival may have depended on a evolution over many generations, this may be a consequence of a subtlied altered body chemistry, there may be some foods that are preferential.
For this reason, fruits that are basic (alkaline) such as apples, grapefruit, or oranges, are frequently favorites, as they seem to aid digestion. Although they are contraindicated in diets designed for people with Celiac problems, the possible culprit is yeast, which as produces a breakdown product, produce furfuric acid which seems to act as a headache or migraine trigger, as well as produce muscle and joint cramps. Foods such as pancakes, or crumpets, which use baking-powder, rather than yeast to rise, seem not to produce any symptoms. These difficulties may occur, as the patient has a metabolism making them susceptible to yeast and fungus infections.
Triggers such as strobe lights apply to both migraines, panic attacks, and epiliform attacks. A minute number of drivers are susceptible to both migraines and, as been demonstrated in France, petit-mal seizures. Usually they are young and in good health, but over-tired from studying.
The general consequences of lupus could apply equally to people who have inherited and/or genetic hypoglycemia but have a high ACTH level for some other reason. Even the treatments for lupus may cause problems.
It has been suggested that whenever the body's state of homeostasis is severely disturbed, that host of diseases may ensue about six months afterward. This may even include the other neuro-degenerative diseases for which there may be a genetic pre-disposition (the use of genetic pre-disposition is deliberate because it is doubtful that a single birth gene defect could produce such a host of diseases later in life, were it not for gene defects, or gene alteration, possibly caused by oxidization-which in men may cause gene fragments to "splice" into the DNA-which,in turn, could lead to a statistically higher rate of neurological diseases in men) that has not been manifest. That is, when a person is young, their immune system may protect them. Various factors such as genetic defects caused by free-radicals, and pollutants such as lead, or any of the organo-phosphate chemicals may alter that protection leading to a manifestation of the disease.
The patient's eyestrain or being lazy in one eye, might be caused by the necessity of mediation between the conflicting overlapping of the different visual images that couldn't be mediated by the lateral geniculate nucleus 'stereo apparatus. This plays an increase in the body's demand for glucose. There is also a possible link between dyslexia and Meres-Irlan syndrome.
If an attempt is made to train the lazy eye this itself can cause an increase in the hypoglycemia. As it is generally recognized that hypoglycemic nervousness is a precursor or possible alternative to what would otherwise be a migraine trigger, or a trigger for a panic attack, it would seem possible to link excessive nervousness to migraines, and indeed nervous stress is a cause of both headaches and migraines. The nervousness may lead to a series of diagnostic problems, such as pituitary dysfunction, (including an overactive or underactive thyroid), or anemia (low blood iron). Indeed trace-minerals normally present in the body (such as iron, calcium, manganese, chromium, zinc, selenium and others, may require the use of supplements. See the note on Thysellonic anemia.
Stress 4 or extreme panic, manifests itself in an increase CRF (corticotrophin releasing factor) level in the body (see the section on stress) together with a host of related neurotransmitters and the suppression of stress inhibitors themselves. This must be considered during any treatment. (Stress can also cause other immune-system problems, by possibly decreasing the effectiveness of the blood-brain barrier, thus allowing defective DNA or the fragments to affect the brain itself.)
Panic attacks have many physiological similarities to migraines. Blood drains from the stomach and the intestines, (in the process halting peristaltic movement,) to flood the muscles in preparation to fight or flee (in fear). As a consequence, the person has their digestive processes interrupted for a span of time that is dependent upon the duration of the attack. Adrenaline (epinephrine) floods the body to ready it for instant response. The blood pressure rises in order to increase circulation, leading to the possibility of heart attack or stroke. This results in a postponed exhaustion and often a protective loss of short-term memory, after the panic attack. It is protective in that it can lessen any delirious physiological effects.
(Hint: Be sure to develop normal sleep habits as prolonged sleep deprivation may lead to erratic behaviour, confusion, panic attacks, exteme anger, paranoia and, will eventually produce a nervous breakdown.)
This loss in short-term memory, can become habitual, and in this case, breeds' confusion and a feeling of contradiction. This may, in persons who have been able to mask the outward symptoms of anger or panic for years, to develop a feeling of chronic fatigue. The patient's mind can 'forget' the event although it remains buried in he subconscious! The patient may be left with an irrational fear of even talking about what caused the panic in the first place! This can lead to an alteration in the function of the hippocampus. This, in turn, postulated an increased need for vitamin B5, as well as a possible need for the use of vitamin B3 (niacin) to increase the circulation in both hemispheres. as this will increase the glucose level in the blood, tri-valent chromium may have to be added to increase the GTF.
Businessmen and professionals learn through experience, what is important and what is not. The major block to success in any profession is panic
The hypoglycemic exhaustion experienced after an extremely bad headache or a migraine or a panic attack, may result in a prolongation of the hypoglycemia. This may itself increase the duration of the headache, or panic attack until a person "sleeps it off"! In the case of panic attacks, recovery can be more rapid, unless the person learns to cope with the panic. This may require a change of lifestyle, profession or simply a major alteration in sleep patterns.
In some cases, doctors fail to recognize that the patient is literally 'stressed-out' for some reason, with an unstable HPA and cortico-steroid inhibition. Thus, the last thing they should receive is more corticosteroid! Because of their adverse effects to the immune system, corticosteroid are contra-indicated whenever hypoglycemia or lupus has developed!
Many doctors may remember the symptoms that they themselves experienced during the term of their residency. However they may have forgotten, they had to remain functional in spite of their hypoglycemic state. They were required to make immediate decisions in spite of how tired they felt. Many successful businessmen or professional performers are the same.
As parallel thinkers may exhibit excessive parallelism, they may be termed day-dreamers. Or they may exhibit traits such as some degree of manic-depressive behavior and may have never learned that it can be turned into an asset. Serial thinkers regard it as something to be 'cured'. In children the cure is frequently Ritalin. In adults, it may be Prozac. Indeed, if the patient cannot handle the depression by trying to stay awake, by drug or alcohol abuse, they will need treatment in a hospital.
However, when a lupus patient is in a state of panic or in a hypoglycemic condition for whatever cause, (such as the use of antimalarials, or as in the case of the anniversary of a traumatic event) they may be classified as having bipolarism, schizophrenia or some other mental illness. They may be told, "To consult with a psychiatrist before it is too late!" They are understandably, shocked, angry, or even bewildered! The implication is that the patient cased their own illness through some unwitting and/or easily avoidable excess. The patient may even, feeling the distressing effects of the hypoglycemia, have known the symptoms and may have been attempting to sleep more than usual, perhaps as much as ten hours a day. Others may have reduced their workload in a futile effort in attempting to relieve their stress.
Frequently, psychologists, who should, of all professions comprehend how suggestible a lupus patient, when any hypoglycemic state, can induce needless anxiety. The psychologists amass a standard battery of tests that they give to a patient, without understanding that in this day of hospital-based television shows, that their patient my recognize a test, to use an example, for Alzheimer's and be panicked because of it! Some doctors have only received a brief lecture about lupus in their training, and may discount the symptoms. For considering the number of organs that may be affected, it is not without cause that lupus is called "the great pretender".
Lifestyle and childhood factors on the development of lupus: Quite frequently the stress factors of childhood, play a prominent part in the onset of lupus. The parents may have made the child feel that it was unwanted or a burden. As a consequence, an intelligent child may have developed some form of escape mechanism, such a voracious appetite for reading, along with a lack of social skills. Because the treatment for lupus frequently involves the use of antimalarials which can heighten hypoglycemia, there is a n increased need to take "life one-day-at-a-time". This is a way of combating, depression, but is runs counter to running a business where an unusual amount of pre-planning may be necessary!
As an adult, there may, as a direct consequence, been a history of broken
relationships for which the patient feels that the problem was the other
person's fault. This may have led to a state of near chronic depression
because they may have a heightened need to control other people (such bullying
as their husbands). In this sense, they may be termed "control freaks".
Men and women think in different ways. Men tend to take the long-term view of life's problems, whereas women quite prefer to take life one-step-a-time". Obviously, these essential difference in outlooks, can lead to conflicts. As a result, men think of women as being almost hysterical at times, while women find that men don't want to "talk things out". As their viewpoints of life, are different, their needs are different as well! As a result, many doctors can't understand the emotional needs of their women patients, and because they think that their female patients "are crying wolf" far too often!
Where men's occupations require essentially parallel thinking, they quite often have problems caused by these professions! Acting, or comedy are typical! Some of the best comedians are men and men seem to have more problems. Often they are so insecure, they find personal relationships a major problem! The may exhibit addictive behavior patterns such as excessive drinking , or the use of drugs. All of these offer an escape from reality. In much the same way, such persons may become obsessive readers. This can be more befinecial as it can develop the ability to see the patterns in life or in a business. Their memory for names of voices can become phenomenal. These people can become excellent in acting, in teaching, or even in sales!
As most men can have less ability for parallel thought, their problems, when they occur, can be more unexpectedly disruptive to their wives! The results can be broken marriages! Because woman are less prone to "see the forest than see the trees", they are surprised by any real long-term crisis, and lash out in their vicinity! They find that their security is now threatened, forgetting that they may have been partially to blame!
Women and men react differently to shopping. Women find shopping exciting and pleasurable whereas men find it stressful. Recent studies in England seem to be confirmatory. Women seem (to men) unable to reach a decision about what to choose. As a result, they overbuy and have to return things. This also extends to packing for a trip.
Men seem to be able to reach a quick decision, abut to their wives, this seems to make them impulsive!
This may have led other people to eventually break-off emerging friendships, when the realized that the patient couldn't or wouldn't do anything to alleviate their depression. Such a simple change in lifestyle as obtaining enough sleep would have seemed irrational to the patient. The result is predicable, the patient would have formed causal friendships with over avid readers, who, because they themselves were depressed, could empathize with the patient. The diagnostician should look for items such a failed marriages, divorces, loss of custody of children from a failed marriage and similar indications. There may even a number of failed friendships where the patient or the patient's friends sought to capitalize on these bonds, such as by borrowing money, or clothes, without having any thought of returning it or them. Of course this applies to people who seek a victim rather than a true friend. But, as may be appreciated, a major problem can ensue.
The patient may reach the mental state (caused depression which is heightened by lack of sleep), were they are unable to distinguish between friend and foe, and even become paranoid!
Because they themselves can become workaholics, they may demand the same of others. Anyone who says no, by their definition, is an enemy. They feel that everything must be perfect or done perfectly, which makes them poor supervisors. In patient's the quest to become buddies, they allow liberties. When these result in lack of performance, they blame the subordinate. They are literally unable to realize that relationships are a matter of give-and-take. They are inclined to be overgenerous in attempt to impress. When the other party protests, they feel attacked.
This makes marriages a problem, because the depressed patient may attribute an ulterior motive for everything the marriage partner does because, in the patient's perspective, they themselves are not deserving. They may, as a child, made to feel guilty for even existing! They may carry their propensity for guilt into adulthood. Their partner may resist control which may lead to unusual degrees of friction in the marriage. As the patient may by this time have become so self-centered, they fail to realize that their partner has some serious health problem which is real, rather than psychosomatic. As a direct consequence, any real problem can be ignored (in the false perception of the patient) until it leads to a crisis! Even so, to bolster their own lack of self-esteem, they may attempt to avoid their own guilt by transferring the blame to the other person in the relationship! (See section on female-male thought differences).
(Hint: the less processing involved in the processing of food to make it last for a long period of time, the more additives have to be added. Some of these not omly increase shelf life but accumulate in the body for the reason that their stability has an unwanted side effect. In time any mild toxic effect can contribute to health problems. Conisider the effect of cheap synthetic perfumes, they never seem to break down and are so stabile that the side effects on other people can be horrendous.) (Remember the giant pumpkins - the level of l-triptophan - growth hormone was so high that it seem to act like a cancer!)
Once again we have to remember that the use of the antimalarials may have increased the problem by increasing hypoglycemia.
Thus the lupus patient may tend to see everything in black or white; everything is perfect, or everything is wrong! All this may also make it impossible for them to act as supervisors, because, in the long term, they may seek perfection rather than excellence.
Patients who have hereditary hypoglycemia may have, as an essential survival mechanism, developed a taste for high protein foods (such as fish or meat) because they were raised on such a diet. In addition, an unusual hunger for protein may develop because of the constant nervous tension, which, in itself can produce or indicate hypoglycemia. Their low level of Coenzyme Q10 and elevated MAO level, may together interfere with their body's utilization of lipids and protein, and the under-production of the normal levels of serotonin as well as many other essentials to a leading a normal life.
Their hypoglycemic state may ensue because the body may be under stress and be metabolizing an excessive amount of glucose/glycogen. Or as is quite possible, the body is unable to use the protein or lipids on the normal fashion! While symptoms such as chronic fatigue syndrome may develop, the cause of it may be misdiagnosed as the result of nervous exhaustion caused by protracted lack of sleep and/or occupational stress! The hypoglycemia and the resultant demand for insulin, may cause the eventual development of diabetes. Again, check if there is a history of diabetes in the patient's family. As this may have a common factor in the development of lupus, and heart attacks, or indeed, a family history of other neurological problems, a comprehensive work-up may be necessary!
Stress that results in hypoglycemia, can cause a reduction in the body's immune system response. It can result in the activation of several viruses of the herpes virus group including Epstein-Barr virus, the varella-zoster virus, HSV-1, HSV-2, and cytomegaloviruses. What should be of concern to doctors, is a possible link between herpes-zoster amid other neurological diseases such as ALS and MS!
The condition, if there is a high cholesterol level and/or high blood pressure can lead to heart attacks or strokes! Some lipids in the diet are essential such as vitamin E, combined with either borage oil or Efamol. In women, phyto-estrogens in the form of flax-seed oil, with an increase in elemental calcium, are necessary to avoid developing loss of bone-mass after menopause. Insomnia can be a problem and it may be the signal to increase calcium levels! Women and men may argue that as a person grows older, they usually need less sleep. But this results in an increase in hypoglycemia!
If the predisposing cause has been allowed to mature, the sense of personal-body-space may be so altered that because of the hypoglycemia, that a feeling of disassociation (from reality) may have developed.
Where there is post-nasal drip the possibility of a chronic sinus infection exists because of the reduced immune function. This could lead to a further complication from the use of corticosteroid to reduce the inflammation. Neither viruses or yeast infections may be cured by this treatment. The use of antibiotics is worse, as if it a yeast that is involved, the medication may only allow it to run rampant! The doctor may have to resort to a medication for a problem such as candids albicans (Nystatin or Mycostatin) or one of the many prorozas such as Guardia. However, treatment for a protozoa may not be effective as the yeast that caused the problem may still be there!
Persons with a yeast infection may develop a whole host of other allergies because their immune system is struggling to cope! As a result, they may develop a persistent cough, a chemical sensitivity, or even such things as rampant dandruff or thickened toenails! There has been a suggestion that the inclusion of antibiotiotics in animal feed, may actually cause the spread of yeast infections, both in the animal's feed itself, and in the persons eating their meat and drinking their milk!
The ataxia may be combined with reduced exercise from the feeling of fatigue (hypoglycemia), to cause a reduction in pulmonary function causing bronchial complications - the patient has been reduced to a more sedentary lifestyle. Respiratory infections could be complicated by the lowered pulmonary function. Indeed pneumonia and TB has been linked to familial or stress-induced hypoglycemia. Expect increased coughing to be required to clear the bronchi of mucus.
Other related symptoms may follow, including a papery dry texture to the skin caused the hypoglycemia that compounds the skin condition of lupus. Remember the comments on yeast infections.
The change to more sedentary lifestyle, when combined with the lowered glucose level and the resulting nervousness, combined with the mild depression to trigger an increased hunger that can cause an instability in weight! Consider the role of too much insulin!
If the patient seems listless and unusually tired and, the hypoglycemic state might be increased by chronic fatigue syndrome 2or vaso-depressor-syncope 3.
If tunnel vision is combined with vertigo, the patient may have a fear of heights. The hypoglycemia may have developer to the degree that the patient may report sudden attacks of vertigo or ataxia when he/she goes out into brilliant sunlight and has to glance down, especially onto a wet or shiny surface. This itself, can lead to panic.
Other indications may be if the patient finds it hard to relax in a brightly lit area. Does the patient seem unusually at ease in rooms or areas with dim lighting? These are subtle indicators and may be due to other factors altogether. With lower lighting levels there may be much less eyestrain. Both afford the patient some relief from the distressing side effects of the lupus. Again hyperglycemic depression is a possible cause but the other factor is that as the body's immune system is very marginal, exposure to sunlight or ultra-violet radiation can produce such a fierce attack on the body's immune system, that the results are self-evident to the patient. Otherwise, when persons are diagnosed with lupus, they are cautioned against exposing themselves to prolonged sunlight, as it causes a reoccurrence!
The effect of adaptation to new eyeglasses may be present to an unusual degree in lupus patients. Typing may result in a consistent pattern of errors being made because the patient may have dyslexia. Indeed, the patient may have been unable to learn to type.
With a hypoglycemic person tries to strengthen a weak eye, the result may be an increase in their hypoglycemia. This is caused by the increase in effective visual field requiring that the brain required more glucose to function. Whenever such a person tries to use variable focal length eyeglasses, they may experience severe nausea, disorientation, and panic. All are signs of a dramatic increase in hypoglycemia!
If the patient has had alternating occurrences of constipation and diarrhea caused by a more-or-less constantly upset stomach this could indicate hypoglycemic stress causing, through insufficient bile acids, flatulence, indigestion, and stomach pain which in itself can prevent a sound sleep. When a patient compounds this by staying awake at night, or is in the habit of watching excessive amounts of TV, or listening to excessive talk-show radio, without a compensatory amount of catnaps, or sleep periods during the day, their hypoglycemia and panic will get worse!
Insufficient bile acids are implicated in asthma, pancreatic distinctions (including cancer), and lung problems. It is a consequence of the depletion of pancreatic gluthiaone which can be normalized by selenium. AA14
As stated, the development of lupus requires a combination of factors, including a lowering of the body's immune threshold, the presence of certain types of genetic material that is almost fits the template of something for which the body has already developed an immunity.
Question whether any neurological symptoms are typical of right brain or left brain dysfunction; or could they be some of both? They may even alternate!
Right brain dysfunction's include; left body weakness or paralysis; difficulty with dressing; spatial tasks; perceptual deficits including poor understanding of what's being seen; quick impulsive behavior in contrast to former deliberate manner; memory flaws including difficulty in remembering dates, appointments; math; many motor skills; frequent stumbling; inability to tell whether standing upright or leaning; problems in positioning - misses buttons; unsafe driving or crossing streets; poor judgment about their own capacities - ignoring defects and displaying overconfidence; comprehension of oral communications but not visual clues; needs constant feedback to relearn tasks.
Left brain dysfunction's include: right body weakness or paralysis; a slow cautious manner in contrast to their former confidence; disarithia - difficulty in clearly articulating words; swallowing problems; disorganized way of doing familiar actions; language, reading and writing difficulties.
Patients who are hypoglycemic may have problems in brain hemisphere mediation and become either left brain dominant or right brain dominant, accounting for the cyclic nature of manic-depression. This can be 'cured' by drugs, or can, in some people can be turned into an advantage though their recognition that each hemisphere has its own unique abilities. Such a patient may be, by self recognition, have learned meditative guidelines and taught her/himself to 'plan thoroughly in depression and act carefully in manic'. Through the constant application of the meditative guidelines to their own conduct, the may be able to avoid excess in either until, they become second nature!
Otherwise they may, under extreme stress, be diagnosed as having multiple personality disorder, rather than a form of schizophrenia caused by lack of sleep, that can result in faulty hemispherical mediation or bipolar disorder.
The numerous symptoms of both left brain and right brain dysfunction's, may, when combined with the progressive nature of lupus; will result in a possibility an erroneous diagnosis of some other form of nervous system degeneration. Because of the hypoglycemia a variation in the amount of corticosteroid may be presupposed. Cushing's syndrome, or Addison's disease might be suspected.
This may indicate dyslexia or bipolarism. It may be caused by a defect in the arrival time of neural stimuli from the retina which suggests a disfunction in the lateral geniculate neuculus. A possible complication is Meares-Irlan's Syndrome.DM.00This is treated by selecting a specific color for the patient's eyeglasses by trial and error. In this manner, the bandwidth of the neural signal is limited, allowing the stress level to be diminished and the vertigo to to be controlled.
This can be seen in patient's who have been treated with lithium. However it parallel's some of the symptoms of vitanin B6 overdose. This abberation extends to treatment with hypercaria perphorai (St. John's Wart). This is sometimes combined with Ginko Bilboa.
Vertigo may be present, other possibilities for misdiagnosis to guard against - might be Méirère's disease or even a protozoic infection such as guardiasis.
Thyroid, pancreatic, or adrenal problems may indeed be involved in the low blood sugar or the hypoglycemia may be a function of more than one of them. In the case of a presupposed thyroid dysfunction, the patient's diet must be checked. Frequently, salt was avoided as the parents "knew it was bad"! Unfortunately for some doctor's diagnosis, salt was iodized for protection against goiter, of thyroid dysfunction. A common sign is a craving for shellfish to increase the iodine in the body, which has been overlooked. Kelp supplements are needed to boost the level of iodine.
An MRI might also reveal an enlarged pituitary, adrenal glands or thyroid. This may have caused the predisposition to the lupus, may have been caused by the patient's history of chronic stress 4 or be familial.
In any case, the result is the hypothalamus's demand for hormones produced by the anterior and posterior pituitary such as ACTH (corticotrophin), somatropen - growth hormone (GH), thyroid stimulating hormone (THS), prolactin (PRL), leutinizing and follicle stimulating hormone (LH/FSH). LH/FSH are vital in reproduction. As hypothalamic somostasin and dopamine inhibit the release of GH and PRL which in turn causes a deficiency in immune response. In turn their deficiency further reduces the immune system's ability to handle further stress.
An increase in the production of CRF (corticotrophin releasing factor) results in a concomitant release of a host of other hormones, such as ACTH, PRL, and LH/FSH. CRF also is implicated in stress headaches, migraines, hypoglycemia, and an increase in the body's production of corticosteroid.
Eventually the body is no longer able to attain a state of homeostasis and beneficial hormone production (GH, THS, PRL, LH/FSH) becomes severely diminished or destabilized. The result, in Lupus, is loss or thinning of the hair, loss of muscle strength, a deterioration in the connective tissues particularly in the body's joints leading to severe arthritis, and the connective tissues in the other organs of the body as well, poor blood circulation, and a further reduction in the body's immune response.
If headaches or panic attacks are a factor, it is wise to remember that migraines and panic attacks frequently trigger the vagus nerve to produce the fight or flight reaction. The lupus patient may react accordingly as the fight or flight reaction acts both centrally and peripherally. There is an enhancement of the pathways that mediate arousal, improved alertness, attention span and aggression. There is also a similar reduction in the factors involving feeding, sexual behavior, growth, and reproduction. Hypoglycemia can cause the same frequently trigger the vagus nerve to produce the fight or flight reaction.
The fight or flight reaction was a survival trait. This may indicate why it is especially well developed among parallel thinkers. In its more advanced cases, persons may be manic-depressive when they are under real or imagined stress. Stress requires a release of Glutamide from the muscles of the body. The secret is in developing ways to handle stress so that things are not perceived as always being black or white! Remember part of the art of civilization is learning to see shade of gray. It has been suggested that parallel thinkers are the product of family conflict, where the child, facing inconsistencies between the parental response, grows-up in an unstable environment that forces the child to be constantly seeking patterns. Too much instability develops only cunning rather than developing character per se.
Survival under threats (real or imaginary), and involve an increase in the heart rate, blood pressure, and respiration. They lead to recurrent stress hyperventilation whenever a real or imaginary threat is perceived and this, in turn, can result in the prolongation of the panic attack to the point of fugue.
Short-term memory becomes dysfunctional leading to difficulties in remembering if some essential action was performed. The patient wants everything done immediately because the thing, subconsciously, that the other person will forget because, under the same circumstances, they will forget. Frequently, their problem is ascribed to another member of the patient's family, a friend or friends, or a coworker at the office (transference). If the perception of stress is prolonged, chronic high blood pressure, chronic fatigue, chronic smoking, chronic alcohol abuse, and chronic overeating can result. Because of ingrained habits, what were initially minor disorders, can lead to serious problems and increased hypoglycemia. See the section on stress.
Rather, by using the patient's own overproduction of steroids, as part the treatment, when combined with DNA-damage-controlling antioxidants, the affliction of lupus may be reversed! at the same time, certain vitamins, such as vitamin B6, may not only reverse the tunnel vision brought about by anti-inflammatory drugs such as Chloroquin, DI.00 but cause muscle mass to increase as well. As B6 increases the level of serotonin, it, when combined with an MAOB inhibitor such as items linked to niacinamide, SSRI's or even tyrosine, might relieve the depression. Because too much vitamin B6 may cause ataxia, or serious nerve problems, vitamin B5 should be taken as well. There is also the possibility that an imbalance in the dopamine, may lead to schitzoidal behavior and/or extreme bi-polarism. Lithium is sometimes used as a treatment in these cases, but in some patients, it can cause extreme depression or dyslexia that requires using a reduces spectral distribution of light, in order for the patient to function almost normally.
For obvious reasons, the consumption of alcohol should be discouraged. Because the patient's depression can lead to a dependence upon alcohol , this is a major point in the treatment!
As a first step, it is essential to break the patient's dysfunctional sleep pattern. This may require such things as ensuring that the patient is so tired, that the patient goes to sleep without the recourse to things such as reading of watching TV!
It may also be remotely possible that some other neuro-degenerative diseases may be placed on hold if not placed in remission by using the same treatment technique.
If the patient had a heart condition, extra precautions may be needed as appropriate.
If the patient's heart permits it, a program of exercise is beneficial to cause an improvement in blood circulation will assist the body to rid itself of metabolic products of the stress, the accumulated bronchial mucus caused by a possible sedentary state of the months preceding the discovery of the lupus, and it may provide a psychological focus for the recovery. A great need for understanding and emotional support is vital if the feeling of panic is going to decrease.
Although the normal diagnosis might give a SSRI medication such as Prozac may be needed, the increase in serotonin level itself may could be counter-priductive by increasing the l-tryptophan thus restarting lupus!! A vitamin B-complex is a start on both the efficient use of the available serotonin, as well as imitigating the body's use of serotonin.
A deficiency in Vitamin B6, will stop or hinder the existing vitamin B6 in its ability to produce GH as well a serotonin necessary for the normal body functions. Too much Vitamin B6 can result in a overdose which can lead to ataxia and other problems. (Vitamin B5 should always be taken whenever larger dosages of vitamin B6 are given.) It can also lead to a deficiency in neurotrophin3. This may be a possible linkage to sunlight's UV devastating effect on patients with lupus.
It is now supposed presumed l-tryptophan is linked to auto-immune disease such as lupus, as well as some neurodegenerative afflictions as well. In the newborn there seems to be some chemical that protects the infant from being rejected by the mother's body (as well as the reverse)! That chemical may be present in the placenta as well as the umbilical cord! (See comment on folic acid and vitamin B-12) As the body's normal production of niacin is derived from l-tryptophan, bi-polarism could be present! AA0.1
It will be needed as well as other vitamins. In addition, a lupus patient's depression mihht be relived by a diet high in Tyrosine 10. During recovery, the boost in the level of SSRI effect through the use of Vitamin B6 and B-complex may not be advisable over an extended period of time as a serotonin-like tolerance may develop. In the case of serotonin enhancers such as Prozac, it seems prudent not to rely on major serotonin enhancement because of the side-effects. L-tyrosine (at the 250 mg level) may prove more effective when it is combined with B-complex 100.
A steady pace is best until the patient demonstrates accelerated capabilities. Guard against a Vitamin B6 overdose. If the patient starts to have migranes,or shows evidence of peripheral neuoropathy, lower the level, or stop the vitamin B6 immediately!
Considering the state of central nervous system depression, many apparent psychological anomalies may appear. Usually an anti-depressant is prescribed to cure the problem. It is wise to avoid treating the symptom rather than the underlying cause. In some cases, depression can the result of the hypoglycemia rather than the cause of it! As depression could be the result of a bad sleep pattern, a possible treatment might have considered - increased exposure of the patient's eye to sunlight-balanced light. Because the patient may have photophobic hypoglycemia the wouldn't be wise. A prescription for oral melatonin 8 may be needed, but this may not be effective if the bi-polarism problem has not been addressed! Even the use of vitamins to assist the body to produce more melatonin may be better. Niacinimide together with vitanin B6, should increase the production of melatonin.
In sleep avoidance, not only is the body's natural sleep pattern disturbed, it disturbs the usual cyclic pattern of steady melatonin level 5 increase until, about four AM when the body's surge in cortico-steroid production causes a drop in the melatonin level, and starts the cycle over! For this reason, panic attacks usually occur upon awakening! Therefore, the patient's lack or abberent melatonin, could lead to a cortico-steroid imbalance leasing to arthritis!
Don't ever think that just because a patient has marked hypoglycemia that the patient is always suicidal! Many medical students suffer from hypoglycemia induced by the requisite long hours and the stress of the job. Businessmen face the same long hours and stress. If they are unable to handle the hypoglycemia, they find other jobs!
Palliatives may be needed. There will be a need for extra sleep if chronic sleep deprivation is to be prevented from developing and even that will not be enough! Frequent rest periods or 'cat naps' are a possible solution. It may be necessary to ensure that the patient gets-up immediately on awakening to restore the normal sleep cycle. The 'healing' effect of the melatonin is essential to promote normal tissue renewal and growth although its production is shutoff by the pineal by the first daylight. The patient may have to resort to the use of dark glasses to avoid excessive eyestrain during the initial stages of recovery from the lupus, remembering that the use of the patient's eyes consumes glucose and produces hypoglycemia. After six months to a couple of years, the dark glasses may no longer seem necessary. This is especially true if Aralin (Chloroquin) DI.00 was used in the treatment! If it was used, and if the patient is elderly, extra care may be needed to avoid bone-breaking falls, when descending stairs. Check for possible side effects when cortico-steroid level is high, or when they are used as an anti-inflammitory.
If stress or the treatment thereof, has resulted in some degree of photophobia, have patient use dark glasses during the day. If the patient's apparent bipolarism, is treated with lithium, several unexpected consequences are possible, especially if the depression is because of dyslexia. The patient's dyslexia may return in a particularly severe form! Often treatment with colored glasses to make the vision monochromatic, is necessary, in order to allay the patient's (Menes-Irulen syndrome) vertigo! This may have been agrivated by the use of Chloroquin or similar drugs. Even treatment with lithium can cause this problem!
As hypoglycemic stress, panic, timidity or constant anxiety, was a factor in the development of lupus, be aware that once the patient is in remission there is an excellent chance of them reverting to the same behavior pattern that initiated the development of lupus in the first place. There will be a potential problem unless the pattern of perceiving things as either totally black or totally white has never been resolved!
As an avoidance of stress plays a major role in maintaining the lupus in remission, the patient and family may need counseling.
All should be informed of a technique that can relieve stress and panic, and to some extent, it is a co-factor in the development and recovery from lupus:
A physician will have to confirm what vitamins that might be of assistance during the various stages of the recovery treatment. Vitamin therapy, in itself, is not a cure. It merely assists the body in creating a state of homeostasis with minimal adverse effects.
A note on cancer - A nine year study by the US National Cancer Institute which was conducted by nutritional researchers, and assessing 35,000 people, seemed to show that Vitamins A, C, E and selenium, reduced cancer of all types by 19%, heart disease by 40%, and cataracts by 43%.
Glutamide levels in the body lower with increasing age. Stress causes a serious reduction in Glutamide. The muscle tissue has to break down to release the Glutamide needed to increase the immune system's efficiency. For this reason a L-glutamine supplement (250) may be necessary in addition to the Vitamin B6 supplementation. (See cautionary reference to PABA - DAME).
If necessary, one (250 mg) of L-Glutamine should be taken at bedtime. If the patient is celiac and on a low gluten, gluten can cause migraines. See comment on MSG.
The vitamin and mineral supplements will have to be taken in the morning, (with the exception of second dose of vitamin B5, in the evening) immediately after eating breakfast.The vitamins necessary for the treatment of lupus include; 10,000 IU of Beta-carotene, 75 to 100 mg. of a B-complex, with the addition of at least 100 mg. of vitamin B-6 are needed.
An addition, may be to take a form of Lycopene BA1.1 as a cancer preventive. A possible alternative is cranberry-juice extract in the form of capsules.
Vitamin B6 will counter retinal/eye problems caused if Alavar (choroquin) or Plaquinil (both anti-malarials) was used in the treatment of lupus. An ophthalmologist can tell, by an examination, if the retinal pigments have been affected. Vitamin B6 and B5 will, in certain cases, reverse any eye damage causing tunnel vision or blind spots. The effect of the antimalarials is dosage dependent. In the case of Alavar 400 mg seems to be the threshold. With Plaquinil, it is about 250 mg. Corticosteroids may be contraindicated it there is any family history of seizures. Indeed, some anti-malarials can induce seizures!
The use of these two vitamins will improve both the peripheral vision and the acuteness of the eyes. Vitamin B6 has, as a tradeoff, a moderate increase in any ataxia. Later the separate dosage of B6 may be decreased to 100 mg. The B-complex may be reduced to 50 mg.
There is another co-factor. The use of vitamin B6 together with the vitamin B complex also increase strength promote muscle growth. The patient's co-ordination, while walking may take time to catch up. The vitamin B6 will aid the growth hormone (GH) and seems to increase connective tissue growth as well as improve the possibility of myelin growth in addition.
The increased requirement for protein for muscle development should be allowed for in the diet, and loss of sleep has to be prevented otherwise any hypoglycemia may increase!
A typical 100 mg B-complex contains the following:
Note: Vitamin B5 is used as a treatment for hypoglycemia. During treatment , the patient may feet a high. The normal production of corticosteroids may become unbalanced.. This is why it is vital for the patient to get enough sleep. Normally, as vitamin B5, makes people sleepy, it is vital to induce the patient to avoid a routine where they get less sleep than usual, or the cycle may start over!More calcium may be needed as well as vitamin-D, as the lack of bright sunlight for a lupus patient has to be taken into account. The added calcum will also assist in a normal sleeping pattern!
The mitigation of the residual serotonin by the additional amount of Vitamin B6 will be needed to manage the patient's depression and/or panic attacks. It is suggested that 250 mg of B6 (and 250 mg of B5) may be needed for eighteen to twenty-four months. Then, a reassement should be done to avoid the effects of B6 overdosages. See the comment about l-tyrosine.
As is the case with serotonin based anti-depressants, an constant overdoseage of Vitamin B6 when combined with sleep deprivation, and a lower level of QE-10, can cause hand tremor, slurred speech, blurred vision and even ataxia!
The PABA as well as zinc, may be essential to prevent the sunlight's UV from causing a problem. (Current studies do not appear to link vitamin A, E, beta-carotene, or selenium Ref 1\BA1.11 by themselves to the UV.) What is more probable, is the level of Lycopene might be already too low to withstand any prolonged exposure to sunlight! As is it now known, the level of UV is increasing rapidly due to the depletion of the ozone layer.
PABA may also darken the patient's hair.
Always be sure to take 100 mg. of Vitamin B5 (D-calcium Pantothenate). This vitamin seems to promote healthy hair growth as well as apparently serving to calm the patient and ensuring sleep. Vitamin B5 can apparently overcome the reduced level of leutinizing and follicle stimulating hormone (LH/FSH). Taken just before going to bed, this vitamin, together with hot chocolate is very effective in promoting a restful sleep and combating the adverse effects of stress. A second B5 can be taken at the same time. Vitamin B5 also increases the formation of axial dendrites in the brain. In this way it may counteract the possible reduction in nerve fibers in the spine. However, prilonged high dosages of vitamin B6, may increas the level of peripheral neurophathy, neurithophin 3 may be needed.
Vitamin B6 Problems
Prolonged high dosages of vitamin B6 may increases the level of peripheral neuropathy, Neurithophin 3 may be needed. If anything that resembles a swelling in the joints in knee, stop administering B6 immediately. CoQ 10 has to be stopped.
Even the level of B6 in multivitamin B complex can cause the same problem.
Circulation problems might ensue. Look for increased cortisol levels.
To increase the circulation, take Niacin with a flush relieving additive such as Intositol. The pills are scored and, initially half a Niacin after breakfast and the other half after dinner. Sometimes stress levels are so high that there is the possibilities of bi-polar behavior.(Sads). Because people with Lupus are very sensitive to small amounts of UV, supplementation of Vitamin D is essential.
Another possibility is the use of Ginko Max three times a day.
Caution the patient against excessive force on
the knee joints such as running up and down the stairs.
It is thought that Vitamin B6 when used together with niacinimide cause the body to produce more melatonin however I could not locate any paper on the possibilty.
Taken immediately after breakfast with the other supplements, Folic acid, 0.4 to 1.0 mg, is needed to supplement the leutinizing and follicle stimulating hormone (LH/FSH). Folic acid will also reduce the possibility of stress-induced heart attacks. The folic acid should be used with Vitamin B12 as well as vitamin B6. Together they will reduce the homocystine level DL.00, and reduce the possibility of colon cancer, stabilize the body's production of thyroid stimulating hormone (THS) and prevent anemia. Remember that a supposed healthy diet was one that was low in salt, and therefore in iodine as well! Doctor's may have forgotten that before iodized salt was in general use, hypoglycemic women used to develop goiters on their neck. Therefore, an iodine additive may have to be given! An easily found source of iodine is in Kelp capsules. Quite often some lupus patients who were on a low-salt diet all their lives may have developed thyroid problems! The patient should be assessed for pernicious anemia beforehand otherwise the Folic acid will mask the symptoms.
If nausea and/or vertigo is part of the patient's problem suspect Lactose-intolerance, Celiacism or simply problems in the digestion of complex carbohydrates. Be sure to remember that childhood lactose intolerance may have been masked in a child that was raised on a farm as the un-pasturesized milk contained lacto-bacteria, which Pasteurization killed. Frequently the lack if an enzyme to digest pasteurized milk is so minor that the digestion of many cheeses pose no difficulties. Acidolphus based yogurt's will aid in digestion. A possible indication is yeast or fungus infections which may be extended to skin outbreaks from poison ivy or poison sumac.
A supplement based on a lactobacillus acidolphus may be of use as an addition to yogurt.
Vitamin A in the form of Beta-carotene (5,000 to 10,000 U.I.) a day, is believed to be the optimal dosage. The retinoids are thought to be of benefit in leukemia and other forms of cancer. As the oil level in the epidermis may increase as the patient's health improves, some form pimples or even sebaceous dermatitis may develop if the patient delays taking beta-carotene supplement.
If the patient has Thysellonic anemia (Thyselemia), it is not advised to use iron supplements as without the attendant L-triptophan necessary to metabolize the iron they may be useless. In patients with Thyselemia), anything that increses the iron in the serum, can cause other problems.
The patient should take between 0.500 mgm and 1,000 mgm of vitamin C (a known anti-oxidant), 400 to 800 units of vitamin E, (another known antioxidant that is effective in increasing activity in the sarcoplasmic reticulum - preventing build up lactic acid in the muscles. Poor circulation causes bruising, taken together with the niacinamide in the 100 mG of B-complex, circulation will be improved and this, together with the zinc, will alleviate the bruising. Zinc causes ruptured blood vessels to heal much more quickly.
Lack of proper blood circulation will also cause cramps. Although Vitamin E has been linked to causing minor iron deficiency, as iron is also implicated in heart disease, this may be a side benefit.
Vitamin C requires the presence of flavinoids from Vitamin B2 - as well as vitamin E otherwise it will be destroyed by oxidization. Vitamin E must have selenium in order for the body to metabolize it.
Add gamma-linolenic acid, such as found in a 25 mg. capsule of oil of evening primrose, (black current oil, or borage oil) which has been reported to prevent strokes.
Add 25 mg. zinc in the form of trivalent zinc (a zinc deficiency is
a co-factor in arthritis and some forms of cancer). Zinc is a powerful
antioxidant and a zinc deficiency may be a factor in diabetes. To be effective,
it should be taken with a in vitamin B complex. It is thought that an inbalance
in the mettalloenzimes may be a factor in both rheumatoid arthritus and
osteo-arthritus. See the reference to the recent study at the University
of Nebraska DG.O2
The susceptibility to diabetes may be offset by the once a day chromium picolinate (or vanadium picolinate - Vanadryl). Unfortunately, rheumatoid arthritis does not sem to benefit from this treatment.
The use of Aspartame (tm) may result in an increase in the SED rate and may also lead to a diagnosis of MS!
As women grow older, more calcium will be needed in order to prevent osteoporosis or osteopina. Supplimental calcium and vitamin D will be needed. The normal level of vitamin D may prove insufficient. A possible clue may be found in a marked preference to fish. Vitamin D supplimentation of 2,000 IU may be needed. (there is a suggection that a low level of vitamine D may lead to colal-rectical cancer). It may also be necessesary to add linseed oil as a phyto-estrogen. (See the following paragraph.) Alother supliment that is useful is the Alpha fatty acids - Omega Protect as an example. As a lupus patient is advised to aviod the UV exposure of sunlite, they will have to take a vitanin D suppliment - 2,000 IU as an example. This seems to mitigate SAD's which can strike even in summer months. This may be part of the cyclic depression.
A zinc deficiency is common where foods are grown using artificial fertilizers which are deficient in zinc. Over many years, the zinc becomes depleted in the soil. Zinc also stops the pituitary from producing prolactin (PRL). Prolactin stops testosterone from being produced. Instead, dihydrotestosterone (DHT) is produced. In men, the effect of an increase in the level of the enzyme 5-alpha-reductase which, in turn, causes a increase in dihydrotestosterone; this is the principal factor in prostate enlargement and, presumably, prostrate cancer. However, prolactin may enhance the production of new stem cells and may enhance recovery from a stroke.
In women, prolactin (PRL) plays a different role. Testosterone is also important because it is essential to the sex drive in a woman. After pregnancy, the body produces more prolactin in order that the mother can produce milk. When a mother has been nursng her baby, when it is weaned, the mother's prolactin level should diminish. Indeed, the time for the production of PRL should de reduced several months after birth in order to increase libido.But when the mother doesn't nurse, her prolactin level remains elevated, and there is an increased possibility of the woman developing breast cancer.
If there is a zinc deficiency, and/or the level of l-tryptophan increases, the Lupus may flare-up after the birth of each child disrupts the bodies immune system.
If there is, because of heredity, already sufficient testosterone to make the libido strong anyway, the absence of zinc will not have any adverse effect, other than to increase the possibility of arthritis.
Panax ginseng 11 is thought to increase the production of testosterone.
Flowers of anise (licorice flavor) can be an effective salt replacement in whole or in part. The anise plant Glycerrhizae radix 12, besides lowering cholesterol, also may reduce tumors as well as candida. However, remember that licorice contains salt!
All should be taken after breakfast in order to make their release more gradual . If the reactions are too severe, breakup the separate vitamins into two doses, the second immediatly after lunch. A caution, Eat four or five smaller meals a day. If weight-gain is a problem, the patient may have to reduce the complex-carbohydrate components and use Efamol or Priminol or to reduce the severity of any headaches as well as increase the quantity of dietary protein.
Vitamin B3 (Niacin), in 500 mg doses will also improve circulation. It may have be taken with (PABA) Para-Aminobenzoic acid (100 mg) to mitigate the irritation of the "flush." It is also used, as noted, to treat vertigo when taken with 10 grains of lecithin. It may assist the left and right hemispheres of the brain to work in conjunction by preventing circulatory unbalance. Asmaller dosage (250 mg (time release) will benfit any possible bi-polarism caused by the low level of l-tryptophan.
It was once touted that when PABA is combined with DMAE 6 (di-methyl-amino-ethanol) and L-Glutamine it provides a useful stimulant to memory, and the more beneficial sleep patterns that can reduce hypoglycemia. Together they produce procaine, and, as is the case with lidocane, seem to prevent headaches or migraines as well as being a possible life extension factor.
See the cautionary note on PABA - DMAE (Denol).
Coenzyme factor Q-10 (50 mg) and L-taurine (100 mg) should be considered as a part of the daily supplementation. QE-10 is increased by exercise. Initially, the level of QE-10 is high and seems to be only moderately affected, by the amount of exercise, but as a person passes the age or 20, the level decreases steadily. Exercise seems boost the level of QE-10. If a person has led a sedentary existence because of an affliction such as Lupus, additional QE-10 must be used in order to build up the energy reserve. In this way, an effective level of exercise can be resumed. In a similar fashion, L-taurine is needed.
PABA also may substantially decrease the loss of immune system-function to the UV-component of sunlight, a factor in the development of lupus.
Chromium picolinate (200 uG to 400 uG - depending on body weight) (or vanadium picolinate) will assist in the conversion of glycogen to glucose, as well as increase the GTF (glucose tolerance factor), and this will reduce the patient's hunger. For the same reason, it will reduce the hypoglycemia and the headaches or migraines in addition. A normal GTF is essential in protection against diabetes, a common occurrence when people have lupus or prolonged or hypoglycemia.
In these cases a natural anti-inflammatory such as horseradish, ginger7 or spices such as those containing capsainin 8 may help every time a nausea and/or vertigo attack takes place. As an alternate treatments, for vertigo alone, pressure on the acupuncture P5 point (an inch below the wrist on the inside) may also help. As the bile-acid level may be normal only at breakfast-time, and indigestion may be minimized allowing increased levels of complex carbohydrates and fats.
As mentioned, especially when the patient gets tired, (after a period working or walking in brightly sunlit areas) the fatigue coupled with a reduction in immune response, may make the patient especially prone to ataxia. Where the patient's doctor advises, natural central nervous system remedies such as ginkgo bilboa extract9 (40 mg), taken at least twice a day may also be of assistance.
The patient must be kept warm, otherwise shivering may 'burn' glucose. If the patient is too warm, open a window or set the air-conditioner for a lower temperature. Patients with hypoglycemia are prone to suffer from respiratory problems and, in seeming contradiction, may be heavy smokers because of a craving for nicotinamide 6.4a1, because of its effects on depression (via increasing the dopamine level and the not-apparent need for a MAO suppressant. As (nicotinic acid is vitamin B3), it would suggest that by using either niacinamide or niacin, the smoking addiction may be more readily be broken!
Although, during the recovery, While the vitamins will provide a boost, they won't make the patient into a superwoman (or superman)!
Caution the patient to be sure to get plenty of sleep! Guard against a repetition of the same work habits or conditions that possibly resulted in the development of lupus in the first place. Bad sleep habits are notoriously difficult to break! A high protein-breakfast won't use up as much insulin as a high carbohydrate meal. Even though a diet containing complex carbohydrates may increas energy levels a moderate amount is better. hey are needed to prevent depression, panic, or excessive anxiety, and to avoid being dysfunctional! Thereafter an moderate increase in the serotonin-rich complex carbohydrates may be needed; as l-tryptophan is not properly convereted to serotonin, even though there may be a craving for these foods, digestion may not function properly and gas pains can be a consequence. It may be better to make the foods containing complex carbohydrates part of breakfast rather than at supper time.
Note that there may be a link to cancer though over use of SSRI's.
Check for the consequences of sleep deprivation. Consider that they may be caused by excess in vitamin B6 as well as a major lack in calcium!
The side effects include a loss in the ability to concentrate, a need to repeat everything at least two or three times, a spaced-out quality or manner, constant annoyance or anger, the false perception that other people are angry with them, moodiness, depression and threats of suicide as a means of button-pushing other people into a desired action, a growing of lack of self esteem whenever the patient is rebuffed which, through transference, is thought the other person's real problem
A repetition of the insistence that the patient can't sleep, is a cause for immediate counciling, otherwise the hypoglycemia may erupt! Generally insomnia, might be be caused by a chronically low level of calcium in the body. Indicatations are a ostiopina, and even fractures.A simple way to promote sleep, is to take two Tums and 100 mg of vitamin D ten mintes before bedtime.
If the patient is under prolonged stress, and resorts to other anti-inflammitories, or even other antidepressants, fibrocitus-like pain may develop unless hot baths or hydromassage is used. The apparent fibrocitus/fibromyalgia, may be a sign of anti-inflammitory or antidepressant and/or B6 and/or more especially (niacin) B3 over-dosage with too low a level of folic acid and B12 to counteract the possibility of hyperhomocysteinemia.
Conversely, it may be the consequence of the use of corticosteroid or the body's own overproduction of insulin and corticosteroid through a defective sleep cycle, that have caused minor damage to the shoulder or hip joint!
During treatment, it is not unusual to expect that any trauma to the patient's body, such as a fracture or even a sprain, will cause an increased reaction in the patient's immune system such as to surprise many doctors. Expect therefore:
Before any blood tests are taken, be sure that the patient is carrying some hard candy to use if the patient feels faint!
If the patient has ever had chickenpox, overwork could bring on shingles! This should be interpreted as a 'warning shot across the bow'!
Problems during recovery: The prolonged or excessive use of vitamin B6 (as may be the case with anything involving Serotonin) as a substitute for sleep, can increase depression and bring-on ataxia. It may make any subsequent lupus recurrences, almost impossible to treat! Try taking two Tums as well as Vitamin D to promote sleep.
Be sure that if the patient is taking niacin or at least niacinimide, to lower LDL chloresterol, that there is sufficient folic acid and 12 in the diet. Otherwise injections of B12 may be needed!
Where the references are incomplete, I have chosen to include them contrary to the usual practice, as they may suggest possible leads.
